Özgür Yaşar Akbal1, Barkın Kültürsay1, Uğur Fındıkçıoğlu2, Berhan Keskin1, Doğancan Çeneli1, Seda Tanyeri1, Ali Karagöz1, Süleyman Çağan Efe1, Hacer Ceren Tokgöz1, Zübeyde Bayram1, Cem Doğan1, Nihal Özdemir1, Cihangir Kaymaz1

1Kartal Koşuyolu Yüksek İhtisas Eğitim Ve Araştırma Hastanesi, Kardiyoloji, İstanbul, Turkey
2Kartal Dr. Lütfi Kırdar Şehir Hastanesi, Kardiyoloji, İstanbul, Turkey

Keywords: malnutrition, hypertension, malnutrition score, dipper, non-dipper

Abstract

Objectives: This study was conducted to evaluate the value of CONUT and NRI malnutrition scores in prediction of non-dipper status, compared with other measurements.

Patients and Methods: In this retrospective study, 167 patients who had ambulatory blood pressure measurements in our hospital were included. 109 patients had previous diagnosis of hypertension; 58 patients were non-hypertensive. CONUT and NRI scores were calculated and their association between dipper and non-dipper patterns were examined.

Results: Patients were divided into two groups according to dipper or non-dipper status. The median age of patients with dipper and non-dipper were 50 (45-55, IQR), 51.5 (45-60) respectively. In addition, 109 (65.2%) subjects were hypertensive. Non-dipper status was seen in 93 (57%) patients. Max night BP and mean night BP were higher in non-dipper group (144 (134-160), 133 (119-140) - 126 (115-137); 111 (101-120) P <0.001, respectively). NRI was lower (low value denotes malnutrition) in non-dipper group (59 (55-63), 60.5 (56-72) respectively p:0.008). CONUT any-degree (25 (26.9%), 32 (43.2%), p:0.027. We also performed ROC curve analysis for optimal cut-off threshold to predict non-dipper HT. Optimal cut-off according to Youden index was 0.297, analysis showed cut-off value 57.9, sensitivity 71%, specificity 58.06, positive predictive value 57.61, and negative predictive value 72%.

Conclusion: Our study showed that malnutrition status defined by CONUT or NRI scores are associated with non-dipper hypertension pattern.