Acute Increase in Postoperative White Cell Count Predicts Mortality in Isolated Aortic Valve Replacement Patients

Mehmet Kalender, Mehmet Taşar, Ata Niyazi Ecevi̇t, Okay Guven Karaca, Ahmet Nihat Baysal, Salih Sali̇hi̇

Keywords: Aortic Valve, White Blood Cell Count, Mortality

Abstract

Introduction: Inflammatory reaction after cardiac surgery is well documented. In this study we aimed to investigate association with acute increase in white blood cell count after cardiopulmonary bypass with mortality. Patients and Methods: We included 35 patients with isolated aortic valve replacement procedure with cardiopulmonary bypass during time phrase June 2009 to July 2013. Blood sampled the day before the operation and on postoperative 24th hour. White blood cell counted and preoperative postoperative difference was calculated. Results: Total 35 patients were included to study. 14 (40%) of them were female. Mean age of patients was 61.14±13.25. Mortality observed patients had two fold increase in mean white blood cell count (preoperative/postoperative white blood cell count 4.971±1.11/ 8.19±3.47 p=0.03 95% CI 1.88-8.06/3.88-12.50). Conclusion: Acute increase in white cell count after aortic valve replacement procedure is associated with mortality.