Relationship Between Admission Neutrophil to Lymphocyte Ratio and ST-Elevation Myocardial İnfarction Complicated by Cardiogenic Shock
Elnur Ali̇zade, Sinan Cerşi̇t, Mustafa Bulut, Anıl Avcı, Mehmet Mustafa Tabakcı, Ahmet Güler, Uğur Aslantaş, Mehmet Yunus Emiroğlu, Selçuk Pala
Keywords: Neutrophil to lymphocyte ratio, cardiogenic shock, myocardial infarction, inflammation, atherosclerosis
Abstract
Introduction: Neutrophil to lymphocyte ratio (NLR) is related to the pathogenesis of acute coronary syndromes. The inflammatory process in ST-elevation myocardial infarction (STEMI) may cause an increase in NLR. In this study, we aimed to investigate whether admission NLR is associated with STEMI complicated by cardiogenic shock. Patients and Methods: The study population comprised patients who had presented with acute STEMI. All patients referred underwent routine blood tests, including common blood cell counts, and NLR analysis. Results: STEMI showed characteristics of cardiogenic shock in 100 patients and was uncomplicated in 103 patients. NLR was significantly different between the two groups (9.9 ± 7.9 vs. 6.2 ± 4.3, respectively, p< 0.001). Multiple logistic regression analyses showed that NLR was significantly associated with STEMI complicated by cardiogenic shock (β= 1.07, 95% CI 1.01-1.15, p= 0.03). Conclusion: Our results demonstrated that admission NLR was higher in patients with STEMI complicated by cardiogenic shock. To prove this relationship between NLR and cardiogenic shock, further investigations are needed.