Usefulness of Platelet-Lymphocyte Ratio to Predict Stent Thrombosis in Patients with ST Elevation Myocardial Infarction
Mustafa Oylumlu, Abdulkadir Yıldız, Murat Yüksel, Ahmet Korkmaz, Mesut Aydın, Mehmet Zihni Bilik, Mehmet Ata Akıl, Sıddık Ülgen
Keywords: Percutaneous coronary intervention, platelet to lymphocyte ratio; ST elevation myocardial infarction; stent thrombosis
Abstract
Introduction: Stent thrombosis, an iatrogenic disease, is an important complication of percutaneous coronary intervention (PCI). The platelet to lymphocyte ratio (PLR) has been recently proposed to be a marker of thrombosis and inflammation, mainly in cancer patients. The aim of this study was to determine whether PLR in patients presenting with acute ST elevation myocardial infarction (STEMI) is predictive of the development of stent thrombosis.Patients and Methods: We retrospectively analyzed the clinical, hematologic, and angiographic data of total 201 patients (mean age 59.8±13.1 years, 3 out of 4 were males) who had undergone PCI for acute STEMI and a further control coronary angiography. 54 of them were diagnosed as stent thrombosis and formed the patient group and 147 patients matched with patient group in terms of age, gender, traditional coronary risk factors, stent implantation procedure, and stent type and length formed the control group in whom the stent implanted during primary PCI was found patent in the repeat coronary angiography.Results: The pre-procedural PLR was significantly higher in patients with stent thrombosis compared to patients without stent thrombosis (176±68 vs. 135±62; p