Mehmet Dedemoğlu, Fatih Öztürk, Deniz Günay, Muharrem Dağlı, Ekin Can Çeli̇k, Murat Sezgi̇n, Emre Selçuk, Davut Çekmeceli̇oğlu, Hakan Ceyran

Keywords: Acute kidney injury, congenital heart diseases, pRIFLE criteria

Abstract

Introduction: The aim of this study was to use pRIFLE classification for the determination and staging of postoperative acute kidney injury in patients undergoing pediatric cardiac surgery and to compare of postoperative results between patients with and without kidney injury. Patients and Methods: Between April 2012 and 2013, all patients undergoing congenital heart surgery were retrospectively reviewed. pRIFLE criteria were used for the determination and staging of acute kidney injury. Primary outcome of interest was the determination and staging of acute kidney injury in the postoperative period by pRIFLE criteria and the comparison of postoperative results between patients with and without kidney injury. Results: Hundred and five consecutive patients were included in this study. Forty-five (42.9%) patients with acute kidney injury were defined as group 1 and others as group 2. Mean age was significantly lower in group 1 (p= 0.001). According to the operative data, the mean cardiopulmonary bypass time was significantly higher (p= 0.04) and the hypothermia was significantly lower in group 1 (p= 0.001). No statistically significant difference was observed between the groups in terms of mortality (p= 0.65). The mean duration of mechanical ventilation and intensive care unit stay was significantly higher in group 1 (p= 0.004 and p= 0.04, respectively), but there was no difference between the groups in terms of hospital stay (p= 0.53).Conclusion: There is a high risk of developing acute kidney injury in patients undergoing congenital cardiac surgery and it may affect postoperative outcomes. For this reason, we recommend the use of pRIFLE criteria which are almost costless, easy, and fast, to predict the renal damage for early detection and intervention in acute kidney injury.