Clinical Features and Factors Affecting In-Hospital Mortality of Patients Who Underwent Pericardiocentesis Due To Moderate To Severe Pericardial Effusion

Oktay Şenöz; Volkan Emren; Zeynep Yapan Emren; Ahmet Erseçgin; Ferhat Siyamend Yurdam; Cem Nazlı

doi:10.51645/khj.2021.m165

Oktay Şenöz^¹, Volkan Emren^², Zeynep Yapan Emren^¹, Ahmet Erseçgin^¹, Ferhat Siyamend Yurdam^¹, Cem Nazlı^²

¹Department of Cardiology, University of Bakircay, Cigli Training and Research Hospital, Izmir, Turkey
²Department of Cardiology, University of Katip Celebi, Atatürk Training and Research Hospital, Izmir, Turkey

Keywords: Malignant effusion; pericardial effusion; pericardiocentesis; tamponade

Abstract

Introduction: The aim of this study was to determine the primary etiology of pericardial effusion in patients undergoing percutaneous pericardiocentesis. Possible in-hospital mortality related predictors were also investigated.
Patients and Methods: A retrospective analysis was made of the clinical and laboratory features of 268 patients who underwent pericardiocentesis due to moderate to severe pericardial effusion between January 2009 and March 2020.
Results: The patients comprised 57.5% males and 42.5% females with a mean age of 62.3 ± 15.4 years. Cardiac compression was detected in 220 (82.1%) patients, of which 208 (77.6%) were clinically tamponade and 12 (4.5%) were asymptomatic cardiac compression. The most common symptom was dyspnea (58.6%) and 10.8% of patients were asymptomatic. Pericardial fluid was exudate in 235 (87.7%) patients. The most common causes were malignancy (37.3%) followed by idiopathic (22.1%) and iatrogenic (12.7%) causes. The patients with asymptomatic cardiac compression were more likely to have malignant effusion than those with other etiologies (p= 0.001). In-hospital mortality developed in 37 (13.8%) patients. The independent predictors of in-hospital mortality were determined as follows; etiology other than infectious or idiopathic (OR= 3.447; 95% CI= 1.266, 9.386; p= 0.015), and receiving antithrombotic therapy (OR= 2.306; 95% CI= 1.078, 4.932; p= 0.031).
Conclusion: Malignancy is the most common cause of moderate to severe pericardial effusions. The detection of cardiac compression in asymptomatic patients may be an important indicator of malignancy. Receiving antithrombotic therapy and having a non-idiopathic and non-infectious etiology may be predictors of in-hospital mortality.

Ethics Committee Approval

This study was approved by the NonInterventional Clinical Research Ethics Committee of Katip Celebi University (Decision number: 2021/0088).

Informed Consent

Informed consent was obtained.

Peer Review

Externally peer-reviewed.

Author Contributions

Concept/Design - OŞ, CN; Analysis/Interpretation - OŞ, VE, ZE; Data Collection - VE, AE, FY; Writing - OŞ; Critical Revision - VE, CN, AE; Statistical Analysis - ZE, FY; Overall Responsibility - OŞ; Final Approval - All of Authors.

Conflict of Interest

The authors have no conflicts of interest to declare.

Financial Disclosure

The authors declared that this study has received no financial support.

BibTex	@article{ kosuyolu_heart_j1817, doi = {10.51645/khj.2021.m165}, author = {Oktay Şenöz, Volkan Emren, Zeynep Yapan Emren, Ahmet Erseçgin, Ferhat Siyamend Yurdam, Cem Nazlı}, title = {Clinical Features and Factors Affecting In-Hospital Mortality of Patients Who Underwent Pericardiocentesis Due To Moderate To Severe Pericardial Effusion}, journal = {Koşuyolu Heart J}, year = {2021}, volume = {24}, number = {3}, pages = {221-228}, publisher = {Kartal Koşuyolu High Specialization Training and Research Hospital} }
RIS	`TY - JOUR AU - Oktay Şenöz, Volkan Emren, Zeynep Yapan Emren, Ahmet Erseçgin, Ferhat Siyamend Yurdam, Cem Nazlı PY - 2021 TI - Clinical Features and Factors Affecting In-Hospital Mortality of Patients Who Underwent Pericardiocentesis Due To Moderate To Severe Pericardial Effusion SP - 221 EP - 228 JO - Koşuyolu Heart Journal J2 - Koşuyolu Heart J VL - 24 IS - 3 PB - DO - 10.51645/khj.2021.m165 ER -`
EndNote	`%0 Journal Article %A Oktay Şenöz, Volkan Emren, Zeynep Yapan Emren, Ahmet Erseçgin, Ferhat Siyamend Yurdam, Cem Nazlı %T Clinical Features and Factors Affecting In-Hospital Mortality of Patients Who Underwent Pericardiocentesis Due To Moderate To Severe Pericardial Effusion %J Koşuyolu Heart Journal %D 2021 %V 24 %N 3 %P 221-228 %R 10.51645/khj.2021.m165`
APA	Oktay Şenöz, Volkan Emren, Zeynep Yapan Emren, Ahmet Erseçgin, Ferhat Siyamend Yurdam, Cem Nazlı (2021). Clinical Features and Factors Affecting In-Hospital Mortality of Patients Who Underwent Pericardiocentesis Due To Moderate To Severe Pericardial Effusion. Koşuyolu Heart Journal, 24(3), 221-228. doi:10.51645/khj.2021.m165
MLA	Oktay Şenöz, Volkan Emren, Zeynep Yapan Emren, Ahmet Erseçgin, Ferhat Siyamend Yurdam, Cem Nazlı. "Clinical Features and Factors Affecting In-Hospital Mortality of Patients Who Underwent Pericardiocentesis Due To Moderate To Severe Pericardial Effusion" Koşuyolu Heart Journal, vol. 24, no. 3, 2021, pp. 221-228. doi:10.51645/khj.2021.m165.
Chicago	Oktay Şenöz, Volkan Emren, Zeynep Yapan Emren, Ahmet Erseçgin, Ferhat Siyamend Yurdam, Cem Nazlı. "Clinical Features and Factors Affecting In-Hospital Mortality of Patients Who Underwent Pericardiocentesis Due To Moderate To Severe Pericardial Effusion" Koşuyolu Heart Journal 24, no. 3 (2021): 221-228. https://doi.org/10.51645/khj.2021.m165.
AMA	Oktay Şenöz, Volkan Emren, Zeynep Yapan Emren, Ahmet Erseçgin, Ferhat Siyamend Yurdam, Cem Nazlı. Clinical Features and Factors Affecting In-Hospital Mortality of Patients Who Underwent Pericardiocentesis Due To Moderate To Severe Pericardial Effusion. Koşuyolu Heart J. 2021; 24(3): 221-228. doi:10.51645/khj.2021.m165.
Vancouver	Oktay Şenöz, Volkan Emren, Zeynep Yapan Emren, Ahmet Erseçgin, Ferhat Siyamend Yurdam, Cem Nazlı. Clinical Features and Factors Affecting In-Hospital Mortality of Patients Who Underwent Pericardiocentesis Due To Moderate To Severe Pericardial Effusion. Koşuyolu Heart J. 2021; 24(3): 221-228. doi:10.51645/khj.2021.m165

Clinical Features and Factors Affecting In-Hospital Mortality of Patients Who Underwent Pericardiocentesis Due To Moderate To Severe Pericardial Effusion

Abstract

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