Is It Suitable to Diagnose Acute Rheumatic Fever with Anti-Streptolysin O?

Abstract

In clinical practice, Anti-streptolizin O (ASO) levels are used for diagnosis of Acute Rheumatic Fever (ARF). We investigated to evaluate the accuracy of using ASO in patients with a murmur in physical examination, in patients with a suspicious ARF history and sometimes only in routine examination. When we evaluate 52 patients' data, high ASO levels was not associated with nor valve structures, neither ARF history. Therefore, we showed that using ASO of levels only is an incorrect application for diagnosis of ARF in clinical practice.