The Relationship Between the Gensini Score and Complete Blood Count Parameters in Coronary Artery Disease
Muhammet Raşit Sayın, Mehmet Ali Çeti̇ner, Turgut Karabağ, Sait Mesut Doğan, Mustafa Aydın, Nesimi Yavuz
Keywords: Coronary artery disease; blood platelets; leukocyte count; neutrophils; blood cellcount.
Introduction: The aim of this study was to evaluate the relationship between the extend and severity of coronary artery disease (CAD) determined by the Gensini score and complete blood count parameters (white blood cell, hemoglobin, platelet, mean platelet volume, lymphocyte, neutrophil). Patients and Methods: Ninety patients with CAD underwent coronary angiography (40 females, mean age 61 ± 1.2 years) were included in this study. Patients with acute coronary syndrome and prior cardiovascular disease excluded from the study. The association between the extent and severity of CAD, which were assessed by the Gensini score, and complete blood count parameters was analyzed by a correlation analysis. Results: Coronary angiography revealed, 6 (6.7%) patients had three, 16 (17.8%) patients had two, and 24 (26.7%) patients had single-vessel disease; 44 (48.9%) patients had non-critical stenosis. The mean Gensini score was 19.1 ± 2.1. We found a relationship between white blood cell and neutrophil counts and the Gensini score. There was no relationship between Gensini score and the mean platelet volume and other parameters. Conclusion: The present study supports the hypothesis that inflammation is one of the main component in the pathogenesis of CAD.