Evaluation of the Relationship Between Hemoglobin Levels and Thrombolysis in Myocardial Infarction Risk Score in Patients with Non-ST Elevation Acute Coronary Syndrome

Abstract

Introduction: The relationship between hemoglobin (Hb) levels at admission and the thrombolysis in myocardial infarction (TIMI) risk score in patients with non-ST elevation acute coronary syndrome (NSTE-ACS) was investigated. Patients and Methods: In total, 286 NSTE-ACS patients were included in the study. Hb levels and biochemical parameters were measured at admission. The patients were grouped into the following three groups according to the TIMI risk score: low-intermediate-, and high-risk groups. Results: Hb levels (in g/dL) at admission in low-, intermediate-, and high-risk groups were 13.5 ± 1.9, 12.5 ± 1.9, and 11.3 ± 1.9, respectively (p < 0.001). We found a negative moderate correlation between Hb levels and TIMI risk scores (r= -0.408, p < 0.001). In univariate regression analysis, it was found that with the increase in the TIMI risk score, Hb levels at admission were significantly reduced (estimate= -0.406; p< 0.001; 95% confidence interval; -0.521 to -0.290). Conclusion: We found that as the TIMI risk score of patients admitted to hospital presenting with NSTE-ACS increased, their Hb levels at admission correspondingly decreased. Thus, the simple and commonly measured Hb level can be a useful parameter in stratifying the risks of patients presenting with NSTE-ACS during admission.