Ahmet Ferhat Kaya1, Cemalettin Yılmaz2, Mehmet Hasan Özdil1, Serdar Soner3, Mehmet Özbek4

1Department of Cardiology, Muş State Hospital, Muş, Türkiye
2Department of Cardiology, Malazgirt State Hospital, Muş, Türkiye
3Department of Cardiology, Diyarbakır Gazi Yaşargil Training and Research Hospital, Diyarbakır, Türkiye
4Department of Cardiology, Dicle University Faculty of Medicine, Diyarbakır, Türkiye

Keywords: Anxiety; coronary artery disease; depression.


Objectives: The SYNergy between percutaneous coronary interventions with TAXUS and Cardiac Surgery (SYNTAX) score is a quantitative scoring system used to evaluate the severity and extent of the disease in patients with coronary artery disease. Hospital Anxiety and Depression Scale (HADS) is a scale that measures the anxiety and depression levels of patients. The relationship between psychosocial stress and atherosclerosis is well known. In this study, we aimed to examine the relationship between SYNTAX score and HADS in patients who performed percutaneous coronary intervention due to acute coronary syndrome (ACS).

Methods: A total of 130 subjects with ACS were included in our study. The SYNTAX score, which was calculated by two independent interventional cardiologists, was divided into three groups: 0–22, low; 23–32, moderate; 33 and above, high. In our study, patients’ anxiety and depression levels were evaluated with HADS 1 month after ACS.

Results: Of the total subjects, 68, 39, and 23 patients were determined in SYNTAX scores of 0–22, 23–32, and >33 groups, respectively. A significant relationship was observed between the high SYNTAX score and the HADS-depression and anxiety scale (p<0.001, p<0.001, respectively). In the correlation analysis found that, a moderate positive correlation between the SYNTAX score and depression level, and a weak positive correlation between the SYNTAX and anxiety level (r=0.642, r=0.538, respectively).

Conclusion: In our study, we found that HADS and SYNTAX scores were significantly correlated in ACS patients who performed percutaneous coronary intervention.

Cite This Article: Kaya AF, Yılmaz C, Özdil MH, Soner S, Özbek M. Is There a Relationship between Anxietydepression Level and SYNTAX Score in Patients with Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention? Koşuyolu Heart J 2024;27(1):3–8

Ethics Committee Approval

The study was approved by the Dicle University Faculty of Medicine Non-Interventional Clinical Research Ethics Committee (no: 193, date: 14/06/2023).

Peer Review

Externally peer-reviewed.

Author Contributions

Concept – A.F.K., M.H.Ö., C.Y.; Design – A.F.K., M.H.Ö., C.Y.; Supervision – A.F.K., S.S., M.Ö.; Funding – A.F.K., M.H.Ö., C.Y.; Materials – A.F.K.; Data collection and/or processing – A.F.K., S.S., M.Ö.; Data analysis and/or interpretation – A.F.K., M.H.Ö., C.Y.; Literature search – C.Y., A.F.K.; Writing – C.Y., A.F.K.; Critical review – S.S., C.Y., M.H.Ö.

Conflict of Interest

All authors declared no conflict of interest.

Use for AI for Writing Assistance

The authors declared that they did not use artificial intelligence for writing assistance.

Financial Disclosure

The authors declared that this study received no financial support.