Mustafa Yıldız, Sahra Asena Balcıoğlu

Department of Cardiology, İstanbul University-Cerrahpaşa, Institute of Cardiology, İstanbul, Türkiye

Keywords: Inflammation; melatonin; pulmonary hypertension; supplement.


Melatonin, which is secreted principally by the pineal gland at night, affects several cardiovascular conditions including arterial hemodynamics, right ventricle functions, and pulmonary artery functions. Pulmonary hypertension is a hemodynamic and pathophysiological condition defined as an increase of average pulmonary artery pressure exceeding 20 mmHg at rest. In the light of the literature data, as discussed in this study, melatonin and its supplements may play a role in the pathogenesis and treatment of pulmonary hypertension.

Cite This Article: Yıldız M, Balcıoğlu SA. Current Position and Future Perspectives of Melatonin and Its Supplements in Pulmonary Hypertension. Koşuyolu Heart J 2024;27(1):37–39.

Peer Review

Externally peer-reviewed.

Author Contributions

Concept – M.Y., S.A.B.; Design – M.Y., S.A.B.; Supervision – M.Y., S.A.B.; Literature search – M.Y., S.A.B.; Writing – M.Y., S.A.B.; Critical review – M.Y., S.A.B.

Conflict of Interest

All authors declared no conflict of interest.

Use for AI for Writing Assistance

Not declared.

Financial Disclosure

The authors declared that this study received no financial support.