Gökhan Demirci, Serkan Aslan, Ali Rıza Demir, Begüm Uygur, Ayan Işık, Enes Arslan, Mehmet Ertürk

Clinic of Cardiology, Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Research and Training Hospital, İstanbul, Türkiye

Keywords: Atherosclerosis; percutaneous coronary intervention


Introduction: In this study, we aimed to investigate the relationship between the preprocedural logistic clinical SYNTAX score (Log CSS) and major cardiovascular events (MACE) in patients with true bifurcation lesions who underwent revascularization with the double stent strategy.

Patients and Methods: A total of 233 non-ST elevation myocardial infarction (NSTEMI) patients who underwent revascularization with a double stent strategy were retrospectively included in the study. Anatomical SYNTAX score (SS) and log CSS were calculated. The patients were divided into two groups according to the cut-off value determined by ROC analysis. The prediction of two-year MACE with Log CSS was evaluated.

Results: MACE developed in 33.9% of patients with high Log CSS and 8.5% of patients with low Log CSS (p< 0.001). In the Kaplan-Meier survival analysis, the long-term survival of the high Log CSS patients was significantly lower than the low Log CSS group (Log-rank p< 0.001). In multivariate COX analyses, high Log CCS (HR= 3.781; 95% CI= 1.706-8.377; p= 0.001) was the strongest independent predictor of MACE.

Conclusion: Log CSS can be a simple and useful tool to predict the development of MACE in patients with true bifurcation lesions revascularized by percutaneous coronary intervention.

Cite this article as: Demirci G, Aslan S, Demir AR, Uygur B, Işık A, Arslan E, et al. Prognostic value of logistic clinical syntax score in coronary bifurcation lesions treated with double stent technique. Koşuyolu Heart J 2022;25(3):240-249.

Ethics Committee Approval

The study was approved by the Ethics Committee of İstanbul Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital and was performed in accordance with the requirements of the Declaration of Helsinki. (Date: 08/05/2019, De-cision No: A-02).

Peer Review

Externally peer-reviewed.

Author Contributions

Concept/Design - SA, ME, GD; Analysis/Inter- pretation - AD, GD; Data Collection - EA, AI, GD; Writing - BU, GD; Critical Revision - BU, EA, GD; Final Approval - ME, GD; Statistical Analysis - AD, GD; Overall Responsibility - GD.

Conflict of Interest

The authors have no conflicts of interest to declare.

Financial Disclosure

The authors declare that this study has received no financial support.