The Relationship Between Mortality Markers and All-cause Mortality in Left Main Coronary Disease with Percutaneous Coronary Intervention
Ekrem Aksu
, Abdullah Sökmen, Ahmet Çağrı Aykan, Akif Serhat Balcıoğlu, Hakan Güneş, Bayram Öztürk, Sami Özgül
Kahramanmaraş Sütçü İmam University, School of Medicine, Department of Cardiology, Kahramanmaras, Turkey
Keywords: Left main coronary artery; percutaneous coronary intervention; hematological mortality markers; all-cause death
Abstract
Introduction: This study aimed to investigate the relationship between all-cause mortality and markers of hematological mortality in post-procedure follow-up of patients who underwent percutaneous coronary intervention (PCI) due to severe left main coronary artery (LMCA) disease.
Patients and Methods: Between January 2015 and August 2019, a retrospective cohort study was performed based on the data of 166 consecutive patients (43 females, 123 males) who were diagnosed with severe LMCA disease as a result of coronary angiography performed in our clinic. The study population was followed median 631.00 (270.75-1172.00) days, was divided into two groups as deceased (group 1, n= 42, 25.3%) and living (group 2, n= 124, 74.6%).
Results: Fasting blood glucose, blood urea nitrogen (BUN), creatinine, alanine aminotransferase (ALT), aspartate aminotransferase (AST), uric acid, C-reactive Protein (CRP)/Albumin ratio, leukocyte, neutrophil, erythrocyte distribution width percentage (RDW) values were found to be higher (p< 0.05) and triglyceride, total protein, albumin, hemoglobin, hematocrit values were lower in the deceased group (p< 0.05). In logistic regression analysis, statistical significance of all of these parameters disappeared.
Conclusion: Advanced age, presence of chronic renal failure (CRF), FBS, BUN, creatinine, AST, ALT, uric acid, CRP/Albumin ratio, leukocyte, and neutrophil height may be helpful in determining increased mortality risk after percutaneous LMCA interventions.
Cite this article as: Aksu E, Sökmen A, Aykan AÇ, Balcıoğlu AS, Güneş H, Öztürk B, et al. The relationship between mortality markers and allcause mortality in left main coronary disease with percutaneous coronary intervention. Koşuyolu Heart J 2020;23(3):176-82.