Ayça Gümüşdağ1, Koray Demir2, Özlem Yıldırımtürk3, Emrah Bozbeyoğlu3, Ömer Kozan4

1Kafkas University School of Medicine, Department of Cardiology, Kars, Turkey
2Sancaktepe Şehit Prof. Dr. İlhan Varank Training and Research Hospital, Clinic of Cardiology, Istanbul, Turkey
3İstanbul Dr. Siyami Erkek Thoracic and Cardiovascular Surgery Training and Research Hospital,
4Clinic of Cardiology, Istanbul, Turkey Başkent University İstanbul Application and Research Center, Department of Cardiology, Istanbul, Turkey

Keywords: High-degree atrioventricular block; acute kidney injury; left ventricular ejection fraction


Introduction: This study aimed to investigate the predictors of acute kidney injury (AKI) in patients with high-degree atrioventricular (AV) block. To the best of our knowledge, this is the first study to examine the relationship between high-degree AV block and AKI in coronary intensive care unit (ICU).

Patients and Methods: In this retrospective study, 226 patients who were admitted to the coronary ICU of our hospital and diagnosed as high-degree AV block were included. AKI was evaluated according to Acute Kidney Injury Network criteria. Logistic regression analyses were performed to identify the independent predictors of AKI in patients with high-degree AV block.

Results: Patients with high-degree AV block were divided into two groups as with or without AKI. Mean age of the patients was 73 ± 14.61, and 50% of the patients were female. AKI was observed in 34% of the coronary ICU with high-degree AV block. In the present study, in-hospital mortality was 6.2% (n= 14) in all patients. In multivariate analyses, eGFR (OR: 0.944, 95% CI: 0.927-0.960; p< 0.001) and LVEF (OR: 0.952, 95% CI: 0.925-0.980; p< 0.001) were found to be independent predictors of AKI in high-degree AV block patients.

Conclusion: Our study, in which AKI was evaluated in high-degree AV block patients, revealed the frequency and predictors of AKI development in high-degree AV block patients for the first time. We found that reduced LVEF and decreased eGFR were independent predictors of AKI in high-degree AV block patients.

Cite this article as: Gümüşdağ A, Demir K, Yıldırımtürk Ö, Bozbeyoğlu E, Kozan Ö. Predictors of acute kid- ney injury in patients with high-de- gree atrioventricular block. Koşuyolu Heart J 2020;23(3):157-62.