Effect of Localization of Coronary Artery Lesions on Total Perfusion Deficit in Myocardial Perfusion Scintigraphy

Cem Doğan, Zübeyde Bayram, Ferahnaz Çınaral, Abdülkadir Uslu, Rezzan Deniz Acar, Çağatay Önal, Murat Çap, Büşra Güvendi̇, Tuba Unkun, Ahmet Karaduman, Aykun Hakgör, Özgür Yaşar Akbal, Cihangir Kaymaz, Nihal Özdemi̇r

Keywords: Stable coronary artery disease, total perfusion deficit, SPECT

Abstract

Introduction: In the present study, we analyzed patients with stable coronary artery disease (SCAD) by quantitative myocardial perfusion scintigraphy and evaluated the effect of different coronary lesion locations on total perfusion deficit (TPD).Patients and Methods: A total of 133 consecutive patients with SCAD who underwent myocardial perfusion imaging single photon emission computed tomography (SPECT) and conventional coronary angiography according to SPECT results were included in the study. TPD was used as the automated quantification variable.Results: Of the patients, 61 had significant coronary artery disease, and 72 had normal coronary arteries. For the normal, left anterior descending artery (LAD), circumflex artery (CX), and right coronary artery (RCA) groups, the median values were 7% vs. 11% vs. 10% vs. 9%, 4% vs. 6% vs. 7% vs. 4%, and 3% vs. 5% vs. 6% vs. 3% for stress TPD (sTPD), rest TPD (rTPD), and ischemic TPD (iTPD), respectively. There was no statistically significant difference in quantitative analysis (sTPD, rTPD, and iTPD) between the LAD, CX, and RCA groups (p> 0.05).Conclusion: TPD obtained by quantitative analysis method can be used for all coronary artery lesion location.