Evaluation of the Epicardial Fat Tissue Thickness and Serum Omentin Levels in Patients with Cardiac Syndrome X

Abstract

Introduction: The aim of this study was to evaluate the correlation between the epicardial fat tissue thickness (EFTT) and serum omentin levels in patients with cardiac syndrome X (CSX). Patients and Methods: A total of 51 patients with CSX admitted to our clinic were included in the patient group, and 46 healthy subjects were included in the control group. Demographics, routine laboratory tests, and high sensitive C-reactive protein (hsCRP) levels of all patients were recorded. The EFTT was measured with transthoracic echocardiography (TTE). Serum omentin levels were measured with the enzyme-linked immunosorbent assay. Results: The EFTT was significantly higher in the CSX group (p< 0.001). Serum omentin levels were significantly lower in patients with CSX in comparison with the control group (p< 0.001). The median age was significantly higher in the CSX group (p< 0.001). The white blood count and hsCRP levels showed no significant difference between the CSX and the control group (p= 0.46 and p= 0.49, respectively). Conclusion: In our study, we found increased epicardial fat tissue (EFT) thickness and decreased serum omentin levels in patients with CSX, a finding similar with the literature. Thus, increased EFT thickness may play a role in the pathophysiology of CSX by causing a decrease in the serum omentin level.